Nanoassembly of Graphene Oxide for Circulating Tumor Cell Isolation
نویسندگان
چکیده
Integrating nanotechnology with established cancer research provides extraordinary opportunities to find essential breakthroughs in the fight against cancer. Nanowires and nanotubes are among the leading approaches under development for biological applications. Till now, the nanodevices face a key challenge to develop surfaces and structures that can be chemically modified for specific conjugation of proteins with limited non-specific adsorption. Here we demonstrate a microfluidic device with graphene oxide (GO) for selective and sensitive detection of circulating tumor cells aimed at early diagnosis of cancer. The functionalized GO can self-assembly on patterned gold surfaces via electrostatic interactions between functional groups on GO and gold surfaces.
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